Chemical Assessments for Textiles

  • Overview
  • ZDHC
  • ToxFMD®
  • Why Work With NSF?
  • Benefits

Industries, including textiles and apparel, are pushing toward the use of safer chemistry in their operations and supply chains.

Responsible companies want to establish chemical standards and practices that go beyond meeting regulatory minimums. Consumers and organizations are pushing for safer chemical formulations in products, forcing companies to look at the chemicals they use more closely.

NSF’s chemical assessment services allow textile companies to demonstrate compliance with supplier demands and program requirements, without necessarily having to divulge proprietary information to outside parties.

We provide two pathways of reaching Level 1 conformance to the Zero Discharge of Hazardous Chemicals (ZDHC) Programme’s Manufacturing Restricted Substances List (MRSL) Conformance Guidance, including ToxFMD Screened Chemistry® and a third-party toxicological review to the ZDHC MRSL. These programs assess the human and environmental hazards associated with using certain chemicals and formulations.


The Zero Discharge of Hazardous Chemicals (ZDHC) Programme takes a holistic approach to tackling the issue of hazardous chemicals in the global textile, leather and footwear supply chain.

One way of working toward the goal of eliminating the use of priority chemicals is by focusing on a Manufacturing Restricted Substances List (MRSL). The ZDHC MRSL provides a clear list of priority chemicals and specifies the maximum concentration limit of each substance in commercial chemical formulations.

NSF is approved by ZDHC to work with chemical suppliers to indicate Level 1 conformance of their products/inventories to the ZDHC MRSL on the ZDHC Gateway - Chemical Module, performing a third-party toxicological review to screen a product’s chemical formulations.

Information about the review process ZDHC MRSL can be found in our brochure.


ToxFMD Screened Chemistry® Program provides a streamlined platform for chemical hazard assessment and supports claims related to safer chemicals at the formulation level, supporting safer chemical identification and informed substitution. ToxFMD® is an assessment of a chemical formulation’s full disclosure of all intentionally added ingredients (no cutoff threshold level) and residuals present at or above 0.01% of the formulation. The ToxFMD® criteria reviews against various chemical hazard assessment methods such as the U.S. EPA Safer Chemical Ingredients List (SCIL) or Master Criteria, the GreenScreen List Translator® (GS LT) or GreenScreen® for Safer Chemicals (GS), and the ZDHC Manufacturing Restricted Substances List (MRSL, Group B, v. 1.1).

Information about the review process for ToxFMD® can be found in our brochure.

ToxFMD® was originally developed by ToxServices and the ToxFMD® mark is the property of ToxServices.

Why Work With NSF?

NSF International has provided toxicology and chemical risk assessment services to evaluate ingredients, materials and products against NSF/ANSI standards, as well as to U.S. and international regulations, for nearly 30 years. Our experts provide:

  • The experience of over 100,000 product evaluations
  • Expertise in toxicology, regulatory compliance, chemistry, biochemistry, environmental chemistry, microbiology, industrial hygiene and engineering
  • Third-party testing to support over 80 NSF/ANSI certification programs, including EPA Safer Choice, CleanGredients® and Green Screen® 


NSF’s chemical assessment services provide several benefits to textile companies:

  • They provide brands and suppliers with a harmonized approach to managing chemicals during the processing of raw materials within the apparel and footwear supply chain.
  • By using chemical formulations that are in conformance to ZDHC MRSL limits, material suppliers and their customers can be assured that banned chemical substances are not intentionally used during production.
  • Third-party verification of conformance allows manufacturers to demonstrate they have evaluated for, reduced or removed priority hazardous substances from their manufacturing process to meet the ZDHC MSRL criteria.
  • You can demonstrate compliance with supplier demands without needing to divulge proprietary information.

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